Walter K. Schmidt
Professor, Department of Biochemistry and Molecular Biology (BCMB)
Ras oncoprotein activity is strongly influenced by post-translational modifications that occur at the COOH-terminus: isoprenylation, palmitoylation, proteolysis, and carboxylmethylation. Our studies are focused on the enzymes that direct these modifications and range from investigations of enzyme specificity to inhibitor development.
Biosketch: https://www.ncbi.nlm.nih.gov/myncbi/161WiFB1JY/cv/270848/
Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/41088668/?sort=date&direction=descending
- Ras oncoprotein activity is strongly influenced by post-translational modifications that occur at the COOH-terminus: isoprenylation, palmitoylation, proteolysis, and carboxylmethylation. Our studies are focused on the enzymes that direct these modifications and range from investigations of enzyme specificity to inhibitor development.
- https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/41088668/?sort=date&direction=descending